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. Author manuscript; available in PMC: 2022 Sep 3.
Published in final edited form as: Actas Dermosifiliogr. 2009 Dec;100(Suppl 2):49–54. doi: 10.1016/s0001-7310(09)73378-2

Table 1.

Summary of the Five Existing Staging Systems for MCC

Study & year Data Stage I Stage II Stage III Stage IV
Yiengpruksawan, et al. 1991 70 patients 1 institution Local Regional Nodal Distant Metastatic –
Allen, et al. 1999 190 patients 1 institution IA: Local < 2 cm
IB: Local ≥ 2cm		 Regional Nodal Distant Metastatic –
AJCC* (6th edition) 2002 No data Local ≤ 2cm Local > 2 cm Local extradermal deep invasion Regional Nodal Distant Metastatic
Allen, et al. 2005 251 patients 1 institution Local < 2cm Local ≥ 2 cm Regional Nodal Distant Metastatic
Clark, et al. 2007 110 patients 3 institutions Local ≤ 1cm IIA: Local ≤ 1 cm & ≤ 2 positive regional lymph nodes
IIB: Local ≥ 2cm		 > 2 positive regional lymph nodes Distant Metastatic

AJCC: American Joint Committee on Cancer;

*

Includes MCC with 82 other non-melanoma skin cancers in a chapter titled “Carcinoma of the Skin.”