Table 1.
Characteristics at baseline for the study population eligible for rEZR determination (controls and AMD subjects), for only controls, for all AMD subjects and for each of the AMD subgroups.
| Overall Study population (n = 300) | Controls (n = 56) | All AMD (n = 244) | Early AMD (n = 34) | iAMD (n = 167) | Late AMD (n = 43) | |
|---|---|---|---|---|---|---|
| Age [years] | ||||||
| Mean ± SD | 71.2 ± 7.21 | 68.1 ± 6.35 | 71.9 ± 7.21 | 71.7 ± 6.38 | 71.2 ± 7.57 | 74.9 ± 5.59 |
| Median [min, max] | 72.0 [55.0, 88.0] | 68.9 [55.0, 80.0] | 72.0 [55.0, 88.0] | 72.0 [57.0, 82.0] | 72.0 [55.0, 88.0] | 68.0 [55.0, 80.0] |
| Gender [female] | ||||||
| n (%) | 186 (62.0%) | 33 (58.9%) | 153 (62.7%) | 27 (79.4%) | 105 (62.9%) | 21 (48.8%) |
| BCVA [logMAR] | ||||||
| Mean ± SD | 0.12 ± 0.30 | − 0.04 ± 0.08 | 0.15 ± 0.32 | 0.01 ± 0.08 | 0.02 ± 0.10 | 0.77 ± 0.25 |
| Median [min, max] | 0.02 [− 0.24, 1.24] | − 0.06 [− 0.24, 0.14] | 0.04 [− 0.24, 1.24] | 0.02 [− 0.18, 0.20] | 0.02 [− 0.24, 0.68] | 0.84 [0.20, 1.24] |
| rEZR [AU] | ||||||
| Mean ± SD | 36.8 ± 19.0 | 47.6 ± 20.2 | 34.3 ± 17.9 | 42.0 ± 18.9 | 37.0 ± 16.8 | 17.7 ± 9.54 |
| Median [min, max] | 34.3 [8.03, 108] | 43.1 [11.0, 108] | 14.1 [8.03, 99.2] | 34.8 [16.7, 99.2] | 34.6 [8.94, 91.0] | 14.1 [8.03, 50.7] |
AMD age-related macular degeneration, iAMD intermediate AMD, AU arbitrary units, BVCA best-corrected visual acuity, SD standard deviation, rEZR relative ellipsoid zone reflectivity.