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TRAP1 agonists show efficacy in a mouse Fabry model
Age-matched Fabry mice treated with 30 mg/kg ML405 three times/week for four weeks showed a reduced Gb3 storage in the liver (A) plasma (B) kidney (C), and heart (D). Values shown are the average of three replicates, n = 9–10. ∗∗∗p < 0.0005, ∗∗p < 0.001, ∗p < 0.05.
