REAGENT or RESOURCE	SOURCE	IDENTIFIER
Chemicals, peptides, and recombinant proteins
2-diheptadecanoyl-sn-glycero-3- phosphoethanolamine (PE(17:0/17:0))	Avanti Polar Lipids	Cat#830756
N-heptadecanoyl-D-erythro- sphingosylphosphorylcholine (SM(d18:1/17:0))	Avanti Polar Lipids	Cat#860585
1-stearoyl-2-hydroxy-sn-glycero-3- phosphocholine (LPC(18:0))	Avanti Polar Lipids	Cat#855775
2-diheptadecanoyl-sn-glycero-3- phosphocholine (PC(17:0/17:0))	Avanti Polar Lipids	Cat#850360
1-heptadecanoyl-2-hydroxy-sn-glycero-3- phosphocholine (LPC(17:0))	Avanti Polar Lipids	Cat#855676
2-Dioctadecanoyl- -sn-glycero-3- phosphocholine (PC(18:0/18:0))	Avanti Polar Lipids	Cat#850333
1-Hexadecanoyl-2-oleoyl-sn-glycero-3- phosphocholine (PC(16:0/18:1)	Avanti Polar Lipids	Cat#850457
1-(9Z-octadecenoyl)-sn-glycero-3- phosphoethanolamine (LPE(18:1))	Avanti Polar Lipids	Cat#850456
1-Palmitoyl-2-Hydroxy-sn-Glycero-3- Phosphatidylcholine (LPC(16:0))	Avanti Polar Lipids	Cat#846725
triheptadecanoylglycerol (TG(17:0/17:0/17:0))	Larodan	Cat#33-1700
trihexadecanoalglycerol (TG(16:0/16:0/16:0))	Larodan	Cat#33-1610
1-stearoyl-2-linoleoyl-sn-glycerol (DG(18:0/18:2))	Avanti Polar Lipids	Cat#855675
3-trioctadecanoylglycerol (TG(18:0/18:0/18:0))	Larodan	Cat#33-1810
3β-Hydroxy-5-cholestene-3-linoleate (ChoE(18:2))	Larodan	Cat#64-1802
1-hexadecyl-2-(9Z-octadecenoyl)-sn-glycero-3-phosphocholine (PC(16:0e/18:1(9Z)))	Avanti Polar Lipids	Cat#800817
1-(1Z-octadecanyl)-2-(9Z-octadecenoyl)- sn-glycero-3-phosphocholine (PC(18:0p/18:1(9Z)))	Avanti Polar Lipids	Cat#878112
1-oleoyl-2-hydroxy-sn-glycero-3- phosphocholine (LPC(18:1))	Larodan	Cat#38-1801
1-palmitoyl-2-oleoyl-sn-glycero-3- phosphoethanolamine (PE(16:0/18:1))	Avanti Polar Lipids	Cat#852467
3β-hydroxy-5-cholestene-3-stearate (ChoE(18:0))	Larodan	Cat#64-1800
1-palmitoyl-d31-2-oleoyl-sn-glycero-3- phosphocholine (PC(16:0/d31/18:1))	Avanti Polar Lipids	Cat#850757
Depositeddata
Metabolomics raw and analyzed data (this paper)		Metabolomics Workbench: https://doi.org/10.21228/M8P97V, project ID PR001091
RNAseq raw and analyzed data	(Govaere et al., 2020)	NCBI Gene Expression Omnibus (GEO) repository: GSE135251
Genome-scale metabolic liver models (this paper)		BioModels: MODEL2102060002
Software and algorithms
R v3.6.0	Hosted by Vienna, University of Economics	https://cran.r-project.org/
MATLAB 2017b	Mathworks, Inc., (Natick, MA, USA)	https://se.mathworks.com/
Cobra toolbox v3.0	(Heirendt et al., 2017)	https://opencobra.github.io/
RAVEN 2.0 suite	(Wang et al., 2018)	https://github.com/SysBioChalmers/RAVEN
Cytoscape v3.8.0		https://cytoscape.org/
Adobe Illustrator CC 2017		https://www.adobe.com/