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. 2022 Aug 15;25(9):104947. doi: 10.1016/j.isci.2022.104947

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© 2022 The Author(s)

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

Magnetic resonance imaging (MRI) of 3D bioprinted constructs loaded with varying quantities of superparamagnetic iron oxide nanoparticles (SPIONs)

(A–D) GelMA constructs laden with no SPIONs (control) (A), 100 (B), 200 (C), and 500 (D) μg/mL SPIONs were imaged in vitro via MRI. T1 weighted images from top (coronal, left) and T2∗ weighted images from side (axial, right) demonstrated the resulting significant contrast in the magnetic 3D scaffolds. Inset in panel (A, top left) shows the 3D CAD design used to bioprint the scaffolds. Scale bars represent 10 mm.