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. Author manuscript; available in PMC: 2022 Sep 3.
Published in final edited form as: ACS Appl Mater Interfaces. 2021 May 12;13(20):23423–23437. doi: 10.1021/acsami.1c03415

Figure 2.

Figure 2.

Hydrogel composition, CEST properties and rheology. (a) Schematic overview of the tri-component hydrogel as prepared by HA-S and Gel-S cross-linking with PEGDA. (b) Chemical structure of Gel-S showing multiple abundant protons that are exchangeable with water protons and the Z-spectra of the three individual hydrogel components. (c) Average gelation time of composite hydrogels post cross-linking with PEGDA. (d) Percentage swelling of composite hydrogels in PBS at 10 and 20 h incubation post gelation (e) storage modulus (G′) curves of the cross-linked hydrogel components over time at 37 °C. (f) Comparison of maximum storage modulus for different hydrogel formulations near complete gelation. *p < 0.05 between compared groups, #p < 0.05 compared to all groups (n = 5).