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. 2022 Sep 3;11(9):e1402. doi: 10.1002/cti2.1402

Figure 3.

Figure 3

CD68+ and CD163+ TAMs correlate with prognosis and response to treatment of BlCa patients. Kaplan–Meier estimates of OS and/or DSS in BlCa patients stratified by peritumoral CD68 (a), intratumoral CD68 (b) and merge CD163 expression (c). Dichotomisation into low and high expression was based on the respective median values. P‐values were calculated by the log‐rank test. (d) Distribution of CD163 positive percentage, according to response to intravesical chemotherapy (mitomycin). ‘Merge’ refers to the whole‐slide evaluation, considering peritumoral and intratumoral regions together. P‐values were calculated by the non‐parametric Mann–Whitney U‐test; ns P > 0.05, *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001. NR, non‐responders; R, responders.