Fig. 7.

The outcome of docking of the vaccine construct and TLR2 receptor. A The three-dimensional structure illustrates the interaction of the construct and TLR2 that are shown in colored parts and harbor blue, respectively. TLR2 and vaccine interacted with each other via the truncated N-PepO (yellow part). B The Dimplot 2D-interaction plot demonstrates the formation of hydrogen bonds between the construct residues (Met¹, Thr², Asp⁶, Tyr⁹, Asp¹⁰, Asn¹³, Asp³⁴, Asp³⁶, Gln³⁷, Glu⁴⁰, Trp⁵⁰, and Glu⁵⁸) and TLR2 residues (Pro³²⁰, Arg³²¹, Tyr³²³, Lys³⁴⁷, Glu³⁷⁴, Gln³⁹⁶, Lys⁴⁰⁴, Ser⁴²⁴, and Arg⁴⁴⁷). PepO residues, TLR2 residues, hydrogen bonds, and non-bonded residues are indicated in green, blue, green dashed lines, and red/pink eyelashes, respectively