Table 1:
Twenty-Five Most Commonly Prescribed Medications on Hospital Admission
| Medication | Occurrences | Metabolic Pathway(s) |
|---|---|---|
|
| ||
| Trazodone | 34 | CYP3A4 |
| Gabapentin | 33 | Not metabolized |
| Levothyroxine | 25 | Not significant CYP450 |
| Atorvastatin | 22 | CYP3A4 |
| Duloxetine | 21 | CYP1A2, CYP2D6 |
| Bupropion | 20 | CYP2B6, also inhibits CYP2D6 |
| Clonazepam | 17 | CYP3A4 |
| Pantoprazole | 17 | CYP2C19 |
| Quetiapine | 16 | CYP3A4 |
| Metformin | 13 | Not metabolized |
| Buspirone | 13 | CYP3A4 |
| Prazosin | 12 | Not significant CYP450 |
| Lisinopril | 12 | Not metabolized |
| Aripiprazole | 12 | CYP2D6, CYP3A4 |
| Metoprolol | 11 | CYP2D6 |
| Venlafaxine | 11 | CYP2D6 |
| Montelukast | 10 | CYP2C8 |
| Omeprazole | 10 | CYP2C19 |
| Lorazepam | 10 | Not significant CYP450 |
| Amlodipine | 10 | CYP3A4 |
| Lamotrigine | 9 | Not significant CYP450 |
| Losartan | 8 | CYP2C9, CYP3A4 |
| Mirtazapine | 8 | Minor CYP2D6, CYP1A2, CYP3A4 |
| Topiramate | 7 | Not CYP450 |
| Lurasidone | 7 | CYP3A4 |