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. Author manuscript; available in PMC: 2022 Sep 4.
Published in final edited form as: J Psychiatr Res. 2020 May 10;126:105–111. doi: 10.1016/j.jpsychires.2020.05.002

Table 2:

Distribution of Phenotypes and Mean Number of Medications on Admission by CYP450 pathways

Mean number of enrollment medications metabolized by pathway (±SD) Poor Poorintermediate Intermediate Intermediatenormal Normal Rapid Ultrarapid
CYP1A2 0.3 (±0.5) 0 (0%) 0 (0%) 0 (0%) 0 (0%) 9 (12.0%) 66 (88.0%) 0 (0%)
CYP2B6 0.3 (±0.4) 0 (0%) 8 (10.7%) 19 (25.3%) 16 (21.3%) 29 (38.7%) 3 (4.0%) 0 (0%)
CYP2C19 0.6 (±0.6) 1 (1.3%) 0 (0%) 16 (21.3%) 7 (9.3%) 23 (30.7%) 19 (25.3%) 9 (12.0%)
CYP2C9 0.2 (±0.4) 0 (0%) 1 (1.3%) 4 (5.3%) 14 (18.7%) 56 (74.7%) 0 (0%) 0 (0%)
CYP2D6 1.2 (±0.9) 3 (4%) 8 (10.7%) 20 (26.7%) 15 (20.0%) 28 (37.3%) 0 (0%) 1 (1.33%)
CYP3A4 2.4 (±1.3) 0 (0%) 0 (0%) 0 (0%) 7 (9.3%) 68 (90.7%) 0 (0%) 0 (0%)
CYP3A5 0.1 (±0.2) 64 (85.3%) 0 (0%) 10 (13.3%) 0 (0%) 1 (1.3%) 0 (0%) 0 (0%)