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. 2022 May 27;226(4):723–728. doi: 10.1093/infdis/jiac219

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© The Author(s) 2022. Published by Oxford University Press on behalf of Infectious Diseases Society of America.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 1. — Trial and cohort characteristics of 15 Staphylococcus aureus bacteremia (SAB) randomized-controlled trials (RCTs). A, Details of SAB RCTs. The size of the bubble is proportional to the number of participants in the control arm. Bubbles are colored according to the inclusion of methicillin-susceptible S aureus (MSSA), methicillin-resistant S aureus (MRSA), or both. B, Cohort characteristics reported in included trials. C, Variability in cohort characteristics between trials. Cells in the heatmap are shaded by z-score. Only variables reported in >50% trials were included. Blank cells represent missing values. APACHE, Acute Physiologic Assessment and Chronic Health Evaluation; IV, intravenous; MLST, multilocus sequence type; PWID, person who injects drugs; SSTI, skin and soft tissue infection.