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. 2022 Jul 25;226(4):566–575. doi: 10.1093/infdis/jiac307

Figure 3.

Figure 3

NK cells show altered expression of NKRs in cCMV-positive newborns. Frequency of NK cells expressing NKG2A, NKp30, NKG2C, CD57, and LILRB1 in cord blood derived from cCMV-positive (n = 16) and cCMV-negative (n = 69) newborns. NK cells are defined as lymphocytes > single cells > CD3−/CD14−/CD19−/CD7+ > CD56+ and/or CD16+. For NK-cell gating strategy refer to Figure 1A. Individuals with < 2% of their total NK cells expressing NKG2C+ are highlighted in red/below dotted line in the NKG2C panel. Axes for % CD57+ and % LILRB1+ range from 0% to 50%. *P < .05, **P < .01, Wilcoxon rank sum test. Abbreviations: cCMV, congenital cytomegalovirus; NK cell, natural killer cell; NKR, NK receptor.