Table 4.
Anti-microbial activity (MIC in μg/mL) of novel synthesized compounds
| Test compound | Minimum inhibitory concentration (µg/ml) | |||||||
|---|---|---|---|---|---|---|---|---|
| M. luteus MTCC 2470 | S. aureus MTCC 96 | S. aureus MLS-16 MTCC 2940 | B. subtilis MTCC 121 | E. coli MTCC 739 | P. aeruginosa MTCC 2453 | K. planticola MTCC 530 | C. albicans MTCC 3017 | |
| 7a | > 125 | > 125 | > 125 | > 125 | > 125 | 3.9 | > 125 | > 125 |
| 7b | > 125 | > 125 | > 125 | > 125 | > 125 | 3.9 | > 125 | > 125 |
| 7c | 3.9 | 3.9 | 3.9 | 3.9 | 3.9 | 3.9 | 3.9 | 3.9 |
| 7d | 3.9 | 3.9 | > 125 | 3.9 | 3.9 | 3.9 | 3.9 | 3.9 |
| 7e | 3.9 | 3.9 | 3.9 | 3.9 | > 125 | 3.9 | 3.9 | > 125 |
| 7f | 3.9 | 3.9 | > 125 | 3.9 | > 125 | 3.9 | 3.9 | > 125 |
| 7 g | 3.9 | 3.9 | > 125 | 3.9 | > 125 | 3.9 | 3.9 | > 125 |
| 7h | 3.9 | 3.9 | 3.9 | 3.9 | 3.9 | 3.9 | 3.9 | 3.9 |
| 7i | 3.9 | 3.9 | > 125 | > 125 | > 125 | 3.9 | > 125 | > 125 |
| 7j | 3.9 | 3.9 | > 125 | 3.9 | > 125 | 3.9 | > 125 | > 125 |
| 7k | 3.9 | > 125 | 3.9 | 3.9 | > 125 | 3.9 | > 125 | > 125 |
| 7l | 3.9 | 3.9 | 3.9 | 3.9 | 3.9 | 3.9 | 3.9 | 3.9 |
| 7m | 3.9 | 3.9 | 3.9 | 3.9 | 3.9 | 3.9 | 3.9 | 3.9 |
| 7n | > 125 | > 125 | > 125 | > 125 | > 125 | > 125 | > 125 | > 125 |
| 7o | 7.8 | 7.8 | 7.8 | 7.8 | 7.8 | 7.8 | 7.8 | 7.8 |
| Miconazole (Standard) | NA | NA | NA | NA | NA | NA | NA | 7.8 |
| Ciprofloxacin (Standard) | 0.9 | 0.9 | 0.9 | 0.9 | 0.9 | 0.9 | 0.9 | NA |
Bold values are related to the high activity and showing good IC50
M. luteus (Micrococcus luteus), S. aureus: (Staphylococcus aureus), B. subtilis (Bacillus subtilis), E. coli: (Escherichia coli), P. aeruginosa (Pseudomonas aeruginosa), K. planticola: (Klebsiella planticola), C. albicans: (Candida albicans), NA (not applicable)