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. 2022 Sep 5;68:104156. doi: 10.1016/j.msard.2022.104156

Table 3.

COVID-19 severity outcomes.

OVERALL
CLADRIBINE
Nr Author N Hospitalization Pneumonia ICU admission Death N Hospitalization Death
01 Louapre C. 347 73 (21.0%) - 4 (1.2%) 12 (3.5%) 3 2 (66.7%) 0 (0.0%)
02 Oreja-Guevara C. 14 1 (7.1%) 1 (7.1%) 0 (0.0%) 0 (0.0%) 14 1 (7.1%) 0 (0.0%)
03 Hervás-García J. V. 19 1 (5.3%) 1 (5.3%) 0 (0.0%) 0 (0.0%) 1^ 0 (0.0%) 0 (0.0%)
04 Salter A. 1626 320 (19.7%) 112 (6.9%) 104 (6.4%) 54 (3.3%) 14 1 (7.1%) 0 (0.0%)
05 Czarnowska A. 396 27 (6.8%) 1 (0.3%) - 1 (0.3%) 5 0 (0.0%) 0 (0.0%)
06 Sormani M. P. 844 96 (11.4%) 99 (11.7%) 38 (4.5%) 13 (1.5%) 11 0 (0.0%) 0 (0.0%)
07 Arrambide G. 326 69 (21.2%) - 7 (2.1%) 7 (2.1%) 6 0 (0.0%) 0 (0.0%)
08 Spelman T. 476 73 (15.3%) - 19 (4.0%) 8 (1.7%) 8 1 (12.5%) 0 (0.0%)
09
Drulovic J. 18 0 (0.0%) 5 (27.8%) 0 (0.0%) 0 (0.0%) 11 0 (0.0%) 0 (0.0%)
10 Fragoso Y. D. 73 15 (20.5%) 20 (27.4%) 6 (8.2%) 2 (2.7%) 1^ 0 (0.0%) 0 (0.0%)
11 Bsteh G. 126 12 (9.5%) - - 4 (3.2%) 2^ 0 (0.0%) 0 (0.0%)
12 Perez A. C. 843 340 (40.3%) - 87 (10.3%) 56 (6.6%) 1^ 0 (0.0%) 0 (0.0%)
13 Yavorskaya V. 30 2 (6.7%) - - 0 (0.0%) 30 2 (6.7%) 0 (0.0%)
POOLED ESTIMATE
Proportion [95% IC] 14.98 [10.47 – 20.97] 8.40 [2.90 – 21.92] 4.44 [2.76 – 7.06] 2.66 [1.79 – 3.92] 9.36 [4.73 – 17.69] 0.00 [0.00 – 1.17]
I^2 [95% IC] 95.48 [89–23 – 98.70] 97.50 [91.71 – 99.64] 88.61 [62.82 – 96.45] 71.23 [30.81 – 90.50] 0.00 [0.00 – 72.22] 0.00
^

Case reports excluded from the meta-analysis