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. 2022 Aug 22;13:947781. doi: 10.3389/fneur.2022.947781

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Copyright © 2022 Duan, Ma, Tan, Miao and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Modules related to the clinical traits of AD. (A) Cluster dendrogram of genes: Heatmap of co-expressed genes. Different colors shown on X and Y axes denote different modules. (B) Heat map of co-expressed genes. Different colors on X and Y axes represent different modules. The depth of yellow color indicates the degree of connection between modules. (C) Dendrogram of Module Eigengenes(MEs) obtained through WGCNA. (D) Correlation between modules and traits. Red and blue represents high adjacency and low adjacency, respectively. PMI, postmortem interval; NFT, neurofibrillary tangle; MMSE, mini-mental state examination.