Table 2.

Univariate and multivariate logistic analysis to determine the independent risk factors of DM in patient with POSNs.

Variables	Univariate analysis			Multivariate analysis
	OR	95%CIs	P–value	OR	95%CIs	P–value
Age
<40 years	Reference			Reference
40–59 years	0.34	0.22–0.52	<0.001	0.98	0.57–1.71	0.953
≥60 years	0.25	0.16–0.4	<0.001	0.93	0.5–1.72	0.815
Sex
Female	Reference
Male	0.92	0.66–1.3	0.647
Race
Black	Reference
Other	1.5	0.66–3.4	0.331
White	1.01	0.53–1.93	0.982
Histological type
Osteosarcoma	Reference			Reference
Chondrosarcomas	0.17	0.09–0.3	<0.001	0.39	0.19–0.77	0.007
Ewing sarcoma	1.7	1.06–2.73	0.027	1.48	0.85–2.58	0.17
Chordoma	0.07	0.03–0.16	<0.001	0.08	0.03–0.21	<0.001
Other	0.86	0.46–1.6	0.633	0.93	0.47–1.83	0.823
Grade
Low (well differentiation)	Reference			Reference
High (poor differentiation)	13.85	6.22–30.82	<0.001	5.43	2.19–13.44	<0.001
Unknown	9.05	4.12–19.85	<0.001	6.29	2.47–16	<0.001
T stage
T1	Reference			Reference
T2	2.79	1.92–4.05	<0.001	1.74	0.96–3.15	0.067
T3	7.76	3.56–16.92	<0.001	4.12	1.62–10.47	0.003
N stage
N0	Reference			Reference
N1	7.92	4.04–15.53	<0.001	4.67	2.16–10.09	<0.001
Tumor size
<5 cm	Reference			Reference
5–10 cm	2.29	1.31–4.01	0.004	1.69	0.87–3.3	0.122
>10 cm	4.06	2.33–7.06	<0.001	1.86	0.81–4.25	0.142