Table 4.
Univariate and multivariate Cox regression analysis for identification independent prognostic factors in POSNs patients with DM.
| Variables | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|
| HR | 95%CIs | P–value | HR | 95%CIs | P–value | |
| Age | ||||||
| <40 years | Reference | Reference | ||||
| 40–59 years | 1.39 | 0.85–2.29 | 0.191 | 1.68 | 0.9–3.16 | 0.1048 |
| ≥60 years | 3.01 | 1.88–4.81 | <0.001 | 4.64 | 2.54–8.49 | <0.001 |
| Sex | ||||||
| Female | ||||||
| Male | 1.02 | 0.69–1.5 | 0.93 | |||
| Race | ||||||
| Black | ||||||
| Other | 0.65 | 0.25–1.7 | 0.378 | |||
| White | 0.74 | 0.39–1.43 | 0.372 | |||
| Grade | ||||||
| Low (well differentiation) | ||||||
| High (poor differentiation) | 1.63 | 0.69–3.8 | 0.262 | |||
| Unknown | 0.78 | 0.34–1.81 | 0.562 | |||
| Histological type | ||||||
| Osteosarcoma | ||||||
| Chondrosarcomas | 0.46 | 0.26–0.83 | 0.01 | 0.33 | 0.18–0.62 | <0.001 |
| Ewing sarcoma | 0.26 | 0.17–0.42 | 0 | 0.38 | 0.22–0.67 | <0.001 |
| Chordoma | 0.18 | 0.06–0.5 | 0.001 | 0.1 | 0.03–0.3 | <0.001 |
| Other | 0.51 | 0.24–1.07 | 0.076 | 0.68 | 0.31 −1.52 | 0.3503 |
| T stage | ||||||
| T1 | ||||||
| T2 | 0.99 | 0.65–1.51 | 0.963 | |||
| T3 | 1.24 | 0.64–2.4 | 0.533 | |||
| N stage | ||||||
| N0 | ||||||
| N1 | 1.04 | 0.6–1.8 | 0.881 | |||
| Tumor size | ||||||
| <5 cm | ||||||
| 5–10 cm | 0.49 | 0.24–0.98 | 0.043 | 0.55 | 0.26–1.18 | 0.1252 |
| >10 cm | 0.72 | 0.37–1.41 | 0.334 | 0.8 | 0.38–1.66 | 0.5457 |
| Surgery | ||||||
| No | ||||||
| Yes | 0.58 | 0.37–0.91 | 0.016 | 0.49 | 0.31– 0.79 | 0.0035 |
| Radiotherapy | ||||||
| No | ||||||
| Yes | 0.62 | 0.42–0.9 | 0.012 | 0.82 | 0.54–1.25 | 0.3651 |
| Chemotherapy | ||||||
| No | ||||||
| Yes | 1.08 | 0.63–1.85 | 0.768 | |||