TABLE 1.

Effects of various rates of hypertension on cardiovascular outcomes.

Study	Subjects	Hypertension	Effect	References
Framingham heart study	Women	High normal blood pressure	Increased risk of CHD	Garcia et al. (37)
Framingham heart study	Women	Hypertension stage 1	Increased risk of CHD	Garcia et al. (37)
Framingham heart study	Women	Hypertension stage 2	Increased risk of CHD	Garcia et al. (37)
Framingham heart study	Men	High normal blood pressure	Increased risk of CHD	Garcia et al. (37)
Framingham heart study	Men	Hypertension stage 1	Increased risk of CHD	Garcia et al. (37)
Framingham heart study	Men	Hypertension stage 2	Increased risk of CHD	Garcia et al. (37)
Japanese urban cohort study (Suita study)	Men	High normal blood pressure	Increased risk of MI	Park (38)
Japanese urban cohort study (Suita study)	Men	Hypertension stage 1	Increased risk of MI	Park (38)
Japanese urban cohort study (Suita study)	Men	Hypertension stage 2	Increased risk of MI	Park (38)
Japanese urban cohort study (Suita study)	Women	Hypertension stage 2	Increased risk of MI	Park (38)
Meta-analysis by the Japan arteriosclerosis longitudinal study group	Men	Higher SBP, pulse pressure and average blood pressure	Increased risk of MI (1.2 per 1,000 person-years)	Hussain et al. (41), Sobenin et al. (42), Andersson et al. (43)
Meta-analysis by the Japan arteriosclerosis longitudinal study group	Women	Higher SBP, pulse pressure and average blood pressure	Not increased risk of MI (0.5 per 1,000 person-years)	Hussain et al. (41), Sobenin et al. (42), Andersson et al. (43)