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. 2022 Sep 5;7:51. doi: 10.1038/s41525-022-00326-9

Table 2.

Comparison between Phase II and Phase I rapid ES in the NICU.

[days; median (IQR) unless otherwise noted] Phase II n = 80a Phase I n = 35 p valueb
Diagnostic Yield (number (%)) 22 (28%) 20 (57%) 0.003
Age at genetics consult 10.5 (4, 52) 7 (3, 26.5) 0.236
Interval from NICU admission to genetics consultc 2 (1, 4) 1 (1, 2) 0.114
Interval from genetics consult to sample collection 4 (2, 15.8) 3 (1, 7) 0.119
Interval from sample collection to ES reportd 13 (10, 16.8) 13 (10, 14) 0.333
Interval from genetics consult to ES report 18 (15, 35) 16 (14, 19.5) 0.019
Interval from NICU admission to ES report 20 (16, 29) 17 (15, 19) 0.016
Age at ES report 45.5 (22, 98) 28 (18.5, 53) 0.015

aTwo infants had ES sent at an outside hospital; dates not included in time intervals.

bCalculated using two-tailed Fisher’s exact test or Mann-Whitney test.

cFor infants with initial genetics consult in our institution’s NICU.

dDate of ES report was abstracted as date of final (written) ES report.