Figure 4.

Ectopic expression of sEV-associated miR-6068 increases cell viability, colony formation, and migration. PC-3 and RC77T/E cells were transfected with miR-6068 mimic and non-specific miR as a negative control. After 24h of transfection, transfected cells were trypsinized and seeded for conducting cell proliferation (A, D), colony formation (B, E), and migration (C, F) assays. Representative inserts showing cell colonies and migration of results generated from three independent experiments. *Significance was calculated at P<0.05.