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. 2022 Aug 15;12(8):3829–3842.

Table 1.

Antiproliferative effects of compounds against MV-4-11 and MV-4-11/quizartinib cells

Compound IC50 (nM, Mean ± SD) RF

MV-4-11 MV-4-11/quizartinib
Quizartinib 0.2 ± 0.1 181.8 ± 15.5 1009.4
Crenolanib 2.1 ± 0.1 13.7 ± 0.9 6.6
Gilteritinib 1.5 ± 0.6 47.0 ± 28.0 31.8
Sunitinib 4.1 ± 0.1 23.3 ± 0.8 5.6
Sorafenib 0.7 ± 0.1 1116.0 ± 152.7 1536.8
Paclitaxel 0.4 ± 0.1 0.2 ± 0.1 0.5

Notes: MV-4-11 and MV-4-11/quizartinib cells were treated with different concentrations of compounds for 72 h. Cell survival was analysed by MTT assay. Data are presented as the means ± SD of three independent experiments. RF, resistance factor.