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. 2022 Aug 22;13:953284. doi: 10.3389/fphar.2022.953284

TABLE 1.

In vitro acaricidal activity of 3,4-tetrahydrofuran diester derivatives.

3,4-Tetrahydrofuran diester derivatives Chemical structural formula Time for killing the first/min Time for killing all mites/min Regression equation LC50 / mg·ml−1
Methoxy-2-dodecarbonate-3,4-tetrahydrofuran diester graphic file with name FPHAR_fphar-2022-953284_wc_tfx1.jpg 143.33 ± 16.07A 750.00 ± 17.32A Y=−2.643 + 2.575X 10.031
Methoxy-2-benzoic acid-3,4-tetrahydrofuran diester graphic file with name FPHAR_fphar-2022-953284_wc_tfx2.jpg 16.66 ± 2.89B 134.67 ± 15.28B Y=−2.507 + 1.823X 3.955
Methoxy-2-valeric acid-3,4-tetrahydrofuran diester graphic file with name FPHAR_fphar-2022-953284_wc_tfx3.jpg 71.67 ± 10.41C 643.33 ± 29.63A Y=−2.754 + 2.953X 8.571
Methoxy-2-acetic acid-3,4-tetrahydrofuran diester graphic file with name FPHAR_fphar-2022-953284_wc_tfx4.jpg 43.33 ± 5.77C 233.67 ± 25.17C Y=−1.421 + 1.863X 5.837
Allyloxy-2-octadecarbonate-3,4-tetrahydrofuran diester graphic file with name FPHAR_fphar-2022-953284_wc_tfx5.jpg 210.33 ± 12.28A 920.00 ± 52.43A Y=−3.399 + 2.582X 21.114
Allyloxy-2-dodecarbonate-3,4-tetrahydrofuran diester graphic file with name FPHAR_fphar-2022-953284_wc_tfx6.jpg 163.33 ± 15.33A 823.67 ± 47.68A Y=−3.211 + 2.742x 15.798
Allyloxy-2-benzoic acid-3,4-tetrahydrofuran diester graphic file with name FPHAR_fphar-2022-953284_wc_tfx7.jpg 30.66 ± 6.89B 214.52 ± 20.07B Y=−3.782 + 1.461X 6.729
Allyloxy-2-valeric acid-3,4-tetrahydrofuran diester graphic file with name FPHAR_fphar-2022-953284_wc_tfx8.jpg 45.33 ± 7.53B 315.84 ± 15.28B Y=−3.894 + 3.939X 9.796
Allyloxy-2-acetic acid-3,4-tetrahydrofuran diester graphic file with name FPHAR_fphar-2022-953284_wc_tfx9.jpg 96.67 ± 15.42C 725.43 ± 35.38A Y=−2.968 + 2.550X 13.582
Benzyloxy-2-octadecarbonate-3,4-tetrahydrofuran diester graphic file with name FPHAR_fphar-2022-953284_wc_tfx10.jpg 115.33 ± 10.38A 520.00 ± 45.83A Y = −7.373 + 6.649X 12.443
Benzyloxy-2-dodecarbonate-3,4-tetrahydrofuran diester graphic file with name FPHAR_fphar-2022-953284_wc_tfx11.jpg 94.33 ± 16.07A 450.00 ± 17.32A Y=−8.599 + 8.778X 9.523
Benzyloxy-2-benzoic acid-3,4-tetrahydrofuran diester graphic file with name FPHAR_fphar-2022-953284_wc_tfx12.jpg 5.66 ± 2.89B 45.67 ± 8.28B Y=−0.383 + 2.031X 0.452
Benzyloxy-2- valeric acid-3,4-tetrahydrofuran diester graphic file with name FPHAR_fphar-2022-953284_wc_tfx13.jpg 35.67 ± 7.56C 420.33 ± 46.63A Y=−1.954 + 2.453X 6.542
Benzyloxy-2-acetic acid-3,4-tetrahydrofuran diester graphic file with name FPHAR_fphar-2022-953284_wc_tfx14.jpg 28.33 ± 4.38C 210.67 ± 23.17C Y=−2.211 + 1.363X 4.628
Pentoxy-2- octadecarbonate-3,4-tetrahydrofuran diester graphic file with name FPHAR_fphar-2022-953284_wc_tfx15.jpg 244.33 ± 25.28A 1070.00 ± 51.43A Y=−2.017 + 3.782X 25.114
Pentoxy-2- dodecarbonate-3,4-tetrahydrofuran diester graphic file with name FPHAR_fphar-2022-953284_wc_tfx16.jpg 185.33 ± 23.33A 870.67 ± 50.68A Y=−2.921 + 2.237X 20.210
Pentoxy-2-benzoic acid-3,4-tetrahydrofuran diester graphic file with name FPHAR_fphar-2022-953284_wc_tfx17.jpg 55.66 ± 7.89B 287.52 ± 35.07B Y=−3.570 + 3.564X 11.277
Pentoxy-2-valeric acid-3,4-tetrahydrofuran diester graphic file with name FPHAR_fphar-2022-953284_wc_tfx18.jpg 124.67 ± 15.42C 795.43 ± 43.38A Y=−3.921 + 3.173X 17.213
Pentoxy-2-acetic acid-3,4-tetrahydrofuran diester graphic file with name FPHAR_fphar-2022-953284_wc_tfx19.jpg 60.33 ± 5.53B 420.84 ± 27.28C Y=−4.131 + 3.559X 14.482
Octadecanoic acid-3,3-tetrahydrofuran diester graphic file with name FPHAR_fphar-2022-953284_wc_tfx20.jpg 54.00 ± 5.77A 1440.00 ± 0.00E 1.945
Liquid paraffin 963.50 ± 15.00D 1440.00 ± 0.00E