Table 3. Baseline characteristics and clinical pregnancy outcomes of patients with TSH levels of 3.5 mIU/L.
| Characteristic | TSH ≤3.5 mIU/L | TSH >3.5 mIU/L | P value |
|---|---|---|---|
| No. of cycles | 5,552 | 536 | |
| Age (years) | 31.19±4.10 | 31.33±4.12 | 0.459 |
| Duration of infertility (years) | 5.79±3.90 | 5.94±3.57 | 0.369 |
| BMI (kg/m2) | 21.79±2.71 | 21.90±2.77 | 0.353 |
| Basal FSH (IU/L) | 4.13±7.68 | 3.82±2.89 | 0.367 |
| Basal E2 (pg/mL) | 30.42±113.24 | 33.67±210.13 | 0.562 |
| AMH (ng/mL) | 2.52±2.89 | 2.40±2.16 | 0.366 |
| TSH (mIU/L) | 1.86±0.73 | 4.32±0.53 | 0.000 |
| FT3 (pmol/L) | 4.38±0.45 | 4.42±0.47 | 0.820 |
| FT4 (pmol/L) | 13.52±1.47 | 13.35±1.55 | 0.781 |
| Duration of Gn (days) | 11.26±1.42 | 11.29±1.47 | 0.645 |
| Total Gn dose (IU) | 2,529.06±802.74 | 2,509.23±830.38 | 0.584 |
| No. of oocytes retrieved | 10.02±4.31 | 9.97±4.23 | 0.789 |
| No. of usable embryos (n) | 3.90±2.57 | 3.93±2.65 | 0.856 |
| Endometrial thickness on day of ET (mm) | 10.04±1.74 | 10.03±1.93 | 0.857 |
| Clinical pregnancy rate (%) | 3,268/5,552 (58.86%) | 308/536 (57.46%) | 0.530 |
| Miscarriage rate (%) | 414/3,268 (12.67%) | 48/308 (15.58%) | 0.145 |
| Live birth rate (%) | 2,854/5,552 (51.40%) | 260/536 (48.51%) | 0.200 |
TSH, thyroid-stimulating hormone; BMI, body mass index; FSH, follicle-stimulating hormone; E2, estradiol; AMH, anti-Mullerian hormone; ET, embryo transfer.