Table 4.
Sarcopenia (+), n = 34 | Sarcopenia (-), n = 55 | p value | |
---|---|---|---|
Age (years) | 77.0 [72.8–80.0] | 68.0 [63.0–74.0] | <0.001*** |
BMI (kg/m2) | 22.6 ± 3.7 | 25.8 ± 4.0 | <0.001*** |
Hand-grip strength (kgf) | 16.3 ± 5.1 | 26.8 ± 8.1 | <0.001*** |
Walking speed (m/s) | 0.73 ± 0.28 | 1.02 [0.88–1.15] | <0.001*** |
Knee extension strength (kgf) | 15.3 ± 6.2 | 24.8 ± 9.3 | <0.001*** |
MTH (cm) | 1.74 ± 0.50 | 2.63 ± 0.62 | <0.001*** |
Skeletal muscle mass (kg) | 17.4 ± 3.5 | 23.8 ± 4.7 | <0.001*** |
SMI (kg/m2) | 5.27 ± 0.85 | 7.16 ± 1.14 | <0.001*** |
Body fat mass (kg) | 17.5 ± 5.9 | 20.1 [15.5–23.6] | 0.107 |
Body fat percentage (%) | 32.8 ± 10.7 | 31.1 ± 7.9 | 0.420 |
Myostatin (pg/mL) | 316 [245–540] | 488 [359–702] | 0.008** |
GDF-15 (pg/mL) | 1630 [1034–3946] | 948 [655–1444] | <0.001*** |
BNP (pg/mL) | 320.1 [172.7–770.4] | 92.0 [46.3–302.6] | <0.001*** |
HDL-C (mg/dL) | 56.7 ± 19.8 | 51.6 ± 13.3 | 0.147 |
TG (mg/dL) | 89.8 ± 44.6 | 102.0 [70.0–137.0] | 0.050* |
hsCRP (mg/L) | 0.25 [0.05–0.75] | 0.12 [0.05–0.52] | 0.355 |
eGFR (mL/min/1.73 m2) | 51.3 ± 26.9 | 62.3 ± 23.1 | 0.044* |
Alb (g/dL) | 3.6 ± 0.6 | 4.0 ± 0.5 | 0.001** |
Hb (g/dL) | 11.3 ± 1.6 | 13.0 ± 1.5 | <0.001*** |
Data are shown as mean ± standard deviation, or, where indicated, median and interquartile range. *, p < 0.05, **, p < 0.01, ***, p < 0.001. BMI, body mass index; MTH, muscle thickness; SMI, skeletal muscle mass index; GDF, growth differentiation factor; BNP, brain natriuretic peptide; HDL-C, high-density lipoprotein cholesterol; TG, triglyceride; hsCRP, high-sensitivity C-reactive protein; eGFR, estimated glomerular filtration rate; Alb, albumin; Hb, hemoglobin.