Table 4.
Histopathological features of the vocal fold nodules and polyps stained with HE, Gomori trichrome and PAS.
| Characteristics | Nodule | Polyp | Significance | ||
|---|---|---|---|---|---|
| N | % | N | % | p | |
| Epithelial | |||||
| Hyperplasia | 46 | 82.14 | 34 | 50.75 | 0 |
| Atrophy | 7 | 12.5 | 21 | 31.34 | 0.013 |
| Erosion | 3 | 5.36 | 6 | 8.96 | 0.445 |
| Dysplasia | 0 | 0 | 0 | 0 | 1 |
| Keratinization ortho | 2 | 3.57 | 8 | 11.94 | 0.091 |
| Keratinization para | 19 | 33.93 | 7 | 10.45 | 0.001 |
| Keratinization ortho/para | 2 | 3.57 | 2 | 2.99 | 0.855 |
| Lamina propria | |||||
| Edema | 40 | 71.43 | 66 | 98.51 | 0 |
| Fibrosis | 32 | 57.14 | 11 | 16.42 | 0 |
| Inflammatory infiltration | 28 | 50 | 37 | 55.22 | 0.563 |
| Basement membrane | |||||
| Thickened BM | 56 | 100 | 0 | 0 | 0 |
| BM thin/intact | 0 | 0 | 67 | 100 | 0 |
| BM focal/thickened | 7 | 12.5 | 21 | 31.34 | 0 |
| Vascular characteristics | |||||
| AMD | 5 | 8.93 | 49 | 73.13 | 0 |
| Mild angiectasia | 45 | 80.36 | 14 | 20.9 | 0 |
| Severe angiectasia | 1 | 1.79 | 51 | 76.12 | 0 |
| Recent hemorrhage | 10 | 17.86 | 51 | 76.12 | 0 |
| Hemosiderin | 0 | 0 | 20 | 29.85 | 0 |