Proposed mechanism of API ameliorative effect on AFB1-mediated
toxicities in the hypothalamic–testicular–epididymal axis of an experimental
rat model. SBE-05, SBE-06, and SBE-07 avert AFB1-induced
oxidative and nitrosative stress, inflammation, and apoptosis by attenuating
the activity of inflammatory cytokines, IL-10, altering the activity of
caspase 9 and inhibiting STAT3 signaling. Created by https://app.biorender.com/. (A color version of this figure
is available in the online journal.)