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. 2022 Jun 6;247(15):1301–1316. doi: 10.1177/15353702221098060

Figure 9.

Figure 9.

Proposed mechanism of API ameliorative effect on AFB1-mediated toxicities in the hypothalamic–testicular–epididymal axis of an experimental rat model. SBE-05, SBE-06, and SBE-07 avert AFB1-induced oxidative and nitrosative stress, inflammation, and apoptosis by attenuating the activity of inflammatory cytokines, IL-10, altering the activity of caspase 9 and inhibiting STAT3 signaling. Created by https://app.biorender.com/. (A color version of this figure is available in the online journal.)