Table 2.
Control | AFB1 | AFB1 + SBE-05-D1 | AFB1 + SBE-05-D2 | AFB1 + SBE-06-D1 | AFB1 + SBE-06-D2 | AFB1 + SBE-07-D1 | AFB1 + SBE-07-D2 | |
---|---|---|---|---|---|---|---|---|
Body weight gain (g) | 65.40 ± 6.80 | 62.17 ± 9.41 | 29.00 ± 19.15 # | 51.50 ± 24.69 | 55.83 ± 14.78 | 65.00 ± 16.29 | 70.50 ± 0.88 | 54.67 ± 12.82 |
Testis weight (g) | 2.54 ± 0.16 | 2.43 ± 0.19 | 2.30 ± .0.24 | 2.25 ± 0.05 | 2.38 ± 0.16 | 2.48 ± 0.10 | 2.50 ± 0.21 | 2.48 ± 0.13 |
Relative testes weight (%) | 1.12 ± 0.13 | 1.10 ± 0.06 | 1.24 ± 0.29 | 1.04 ± 0.05 | 1.10 ± 0.14 | 1.09 ± 0.13 | 1.06 ± 0.12 | 1.16 ± 0.13 |
Epididymis weight (g) | 0.43 ± 0.09 | 0.36 ± 0.07 | 0.37 ± 0.04 | 0.37 ± 0.03 | 0.39 ± 0.04 | 0.39 ± 0.03 | 0.50 ± 0.15 | 0.41 ± 0.05 |
Relative epididymis weight (%) | 0.19 ± 0.05 | 0.16 ± 0.02 | 0.20 ± 0.03 | 0.17 ± 0.01 | 0.18 ± 0.01 | 0.17 ± 0.02 | 0.21 ± 0.06 | 0.19 ± 0.02 |
Hypothalamus weight (g) | 0.07 ± 0.02 | 0.07 ± 0.01 | 0.06 ± 0.01 | 0.06 ± 0.00 | 0.06 ± 0.01 | 0.04 ± 0.00 | 0.05 ± 0.01 | 0.05 ± 0.03 |
Relative hypothalamus weight (%) | 0.033 ± 0.014 | 0.031 ± 0.002 | 0.031 ± 0.004 | 0.028 ± 0.008 | 0.028 ± 0.008 | 0.020 ± 0.001 | 0.024 ± 0.005 | 0.028 ± 0.015 |
AFB1: aflatoxin B1; SBE: Sorghum bicolor extract.
AFB1, 50 µg/kg; AFB1 + SBE-05-D1, 0.05 + 5 mg/kg; AFB1 + SBE-5-D2, 0.05 + 10 mg/kg; AFB1 + SBE-06-D1, 0.05 + 5 mg/kg; AFB1 + SBE-06-D2, 0.05 + 10 mg/kg; AFB1 + SBE-07-D1, 0.05 + 5 mg/kg; and AFB1 + SBE-07-D2, 0.05 + 10 mg/kg. Values are expressed as mean (SD) for six rats per group.
Values differ significantly from control (p ⩽ 0.05).
Values differ significantly from AFB1 alone (p ⩽ 0.05).