TABLE 2.
Adherence of wild-type and isogenic mutant strains of M. catarrhalis to Chang conjunctival epithelial cells in vitro
| Strain | Genotype | Adherencea |
|---|---|---|
| 012E | Wild type | 123.0 ± 15.57 |
| 012E.1 | uspA1 mutant | 9.3 ± 3.8 (0.0001) |
| 012E.2 | uspA2 mutant | 138.3 ± 19.6 (0.0088) |
| 012E.12 | uspA1 uspA2 mutant | 14.1 ± 3.8 (0.0001) |
| TTA37 | Wild type | 42.4 ± 17.3 |
| TTA37.1 | uspA1 mutant | 45.8 ± 14.7 (0.6593) |
| TTA37.2 | uspA2H mutant | 6.7 ± 2.1 (0.0003) |
| TTA37.12 | uspA1 uspA2H mutant | 4.5 ± 0.5 (0.0002) |
| 046E | Wild type | 52.1 ± 13.1 |
| 046E.1 | uspA1 mutant | 55.2 ± 14.3 (0.6725) |
| 046E.2 | uspA2H mutant | 45.4 ± 18.1 (0.4847) |
| 046E.12 | uspA1 uspA2H mutant | 6.7 ± 2.2 (0.0001) |
a
Adherence of M. catarrhalis to Chang cells is expressed as the mean (± standard deviation) percentage of the inoculum which adhered to the monolayers. The P value compared to the value for the wild-type parent strain, using a two-tailed t test, is given in parentheses.