Table 3.
Amino acid changes and deletions in SARS-CoV-2 variants of concern and their localization in the selected peptides.
| Peptides | Localization | Alpha (B.1.1.7) | Beta (B.1.351) | Gamma (P.1) | Delta (B.1.617.2) | Omicron (BA.1) |
|---|---|---|---|---|---|---|
| NT-1 RTQLPPAYTNS | 21–31 | – | – | P26S | – | – |
| NT-2 MESEFRVYSSANN | 152–164 | – | – | – |
R158G Δ156–157 |
– |
|
RBD1 SNNLDSKVGGNY |
438–450 | – | – | – | N440K G446S | – |
| RBD2 RLFRKSNLKPFE | 454–465 | – | – | – | – | – |
| RBD3 ISTEIYQAGST | 468–478 | – | – | – |
S477N T478K |
– |
|
RBD4 YGFQPTNGVGYQ |
495–506 | N501Y | N501Y | N501Y | – |
G496S Q498R N501Y Y505H |
| RBD5 GPKKSTNLVKNK | 526–537 | – | – | – | – | – |
|
N MSDNGPQNQRNA |
1–12 | D3L | – | – | – | – |
*Amino acid changes and deletions of each variants were collected from the database CoVariants (https://covariants.org/variants). Δ: Deletion.