Table 10.
Adverse effects of montelukast | ||
---|---|---|
Overall effects | Pharyngitis, fever, infection | Comparable to placebo47 |
Effects on lower airways | Worsening of asthma | Comparable to placebo47 |
Effects on central nervous system | Irritability, aggressiveness, hallucinations Suicide? |
Related to other drugs used together? Symptom improvement after treatment discontinuation48, 49, 50, 51, 52 |
Vascular system | Churg-Strauss Syndrome? (Vasculitis) Angioedema |
Not fully clarified53, 54 |
Skin | Urticaria | 53 |
Hepatic | Hepatitis | 53, 55 |
High doses of up to 1000 g | Malaise, vomiting, abdominal pain and hyperactivity | No serious accounts in relation to overdose56, 57 |