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miR-150-mRNA interactions in HTLV-1 infection/transformation: one confirmed, many to explore. miR-150 is known to repress expression of STAT1 (highlighted in green) when overexpressed in ATLL cell lines (24). As depicted here and described in the text, many other genes of potential relevance to HTLV-1 infection and pathogenesis are known to be controlled by miR-150 in normal and neoplastic T-cells and other leukocyte populations.
