Table 2.

Treatments approaches of ORN used in the last 10 years.

Authors/date	n	Successful treatments	Follow-up (months)
D'Souza et al. (2007)24	23	3 HBO	30 (minimum)
		3 HBO, S
		5 S
Coletti and Ord (2008)27	19	5 S	18 (mean)
Alam et al. (2009)23	33	8 ATB, HBO, S	1–61
		22 ATB, S
Lee et al. (2009)28	13	2 S	6–361
		3 HBO, S
Oh et al. (2009)29	114	4 ATB, HBO	12–382
		7 ATB, S
		18 ATB, NSD
		25 ATB, HBO, NSD
		34 ATB, HBO, S
Delanian et al. (2011)30	54	16 ATB, PENTOCLO	2–36
Hampson et al. (2012)31	411	243 HBO	96
Mücke et al. (2013)32	94	44 ATB, S	12 (minimum)
Niewald et al. (2013)33	11	1 HBO	1–147
		2 NSD
		5 S
Lyons et al. (2014)34	85	3 ATB, PENTO, DNS	3–60
		4 ATB, PENTOCLO
		14 ATB, PENTO
		35 ATB, PENTO, S
Porcaro et al. (2015)35	01	1 ATB, NSD	12
Raguse et al. (2016)36	149	2 ATB	27–54
		6 S
		30 NSD

ATB, antibiotic therapy; S, surgery; NSD, non-surgical debridement; PENTO, pentoxifylline and tocopherol; PENTOCLO, pentoxifylline, tocoferol and clodronate; HBO, hyperbaric oxygenation.