Table 2.
Comparison between the two sedative regimen dosing and adverse effects.a
| Chloral hydrate (n = 73) |
Propofol (n = 117) |
p-Value | |
|---|---|---|---|
| Propofol total dose (mg/kg) | n/a | 5.4 (1.9) | n/a |
| Chloral hydrate dose (mg/kg) | 33.4 (7.7) | n/a | n/a |
| Heat rate pre-sedation | 131.4 (18.4) | 126.3 (22.7) | 0.12 |
| Heart rate after procedure was completed | 115.8 (17.2) | 101.2 (15.4) | <0.0001 |
| Hypoxemia | 1 (1%) | 12 (10%) | 0.0183 |
| Apnea | 0 (0%) | 1 (1%) | 0.43 |
| Oxygen supplementation | 0 (0%) | 10 (9%) | 0.01 |
| Desired level of sedation achieved | 64 (88%) | 117 (100%) | <0.0001 |
| A second dose of medication given | 10 (14%) | n/a |
a
Data presented as Mean (SD) or n (%) as appropriate.