TABLE 2.

Antibiotic susceptibilities of P. aeruginosa strains carrying mutations in mexR

Strain	Relevant genotype	MICa (μg/ml) of:
		CAR	CEF	CAM	TET
K767	Wild type	128	2	64	16
OCR1	nalB	1,024	8	512	64
K1454b	nalC	512	4	256	32
K1455c	nalB	1,024	8	512	64
H103	Wild type	64	2	32	16
K1464d	nalB	512	8	256	64
K1466e	nalC	256	4	128	32
K1482	K767 mexR::ΩHg (SstI)f	256	4	128	32
K1483	K1454 mexR::ΩHg (SstI)	256	4	128	32
K1485	K767 mexR::ΩHg (MluI)	1,024	8	512	64
K1486	K1454 mexR::ΩHg (MluI)	1,024	8	512	64
K1488	K767 ORF2::ΩHg (Tth111I)	128	2	64	16
K1491	K767 ΔmexR (SstI-MluI)	1,024	8	512	64

^aCAR, carbenicillin; CEF, cefepime; CAM, chloramphenicol; TET, tetracycline. 

^bK1459, K1460 and K1489 displayed the same MIC values as K1454. 

^cK1456, K1457, K1458, and K1461 displayed the same MIC values as K1455. 

^dK1462, K1463, and K1465 displayed the same MIC values as K1464. 

^eK1467 and K1468 displayed the same MIC values as K1466. 

^fRestriction sites in parenthesis denote either the position of insertion of the Ω interposon (mercury resistant) or the restriction sites that were used to construct defined deletions.