Chart 1.

Cholesteatoma slides and their association with patient's gender, age, slide number, MMP2 expression intensity and complication (when it happened). - MMP2: matrix metalloproteinase 2.

Initials	Gender	Age	Slide	MMP2 reading	Complication
D.G.P.V.	Male	17 years	B02 14933	++	Lateral sinus thrombosis
R.M.D.S.S.	Male	18 years	B00 07723	++	Left temporal lobe abscess
J.C.D.S.	Male	24 years	B02 28657	++	Meningitis
O.C.D.S.	Male	37 years	B98 09318	+++	Left temporal bone abscess and meningitis
J.P.D.S.	Female	22 years	B01 18345	+++	Sigmoid sinus thrombosis and meningitis
A.P.D.S.	Female	30 years	B02 35536	+++	Sigmoid sinus thrombosis
A. A. S.	Female	35 years	B03 32668	+++	Labyrinthitis and erosion of the facial nerve canal
V.L.B.D.S	Female	32 years	B04 04518	0	Meningitis and peripheral facial paralysis
W.F.P.	Male	16 years	B03 5856	0	No complications
J.D.R.	Male	17 years	B92 408	++	No complications
R.P.	Male	19 years	B03 2724	0	No complications
S.S.L.	Male	66 years	B03 24412	+	No complications
R.D.J.S.	Male	21 years	B03 4079	+	No complications
L.C.S.	Female	15 years	B03-521	++	No complications
E.N.D.	Female	26 years	B03 01011	+	No complications
S.H.V.	Female	32 years	B04 4205	++	No complications
L.G.G.	Female	50 years	B94 7353	+	No complications
S.M.S.B.	Female	38 years	B03 670	+	No complications
M.M.C.D.S.	Female	62 years	B03-1132	+	No complications