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. 2022 Sep 5;2022(9):CD013877. doi: 10.1002/14651858.CD013877.pub3

Comparison 1. Intranasal steroid spray compared to no intervention/placebo.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1.1 Presence of normal olfactory function (as assessed by participants) 1   Risk Ratio (M‐H, Fixed, 95% CI) Subtotals only
1.1.1 ≤ 4 weeks 1 100 Risk Ratio (M‐H, Fixed, 95% CI) 1.19 [0.85, 1.68]
1.2 Duration of olfactory dysfunction 1 100 Mean Difference (IV, Fixed, 95% CI) ‐6.50 [‐7.58, ‐5.42]
1.3 Presence of normal olfactory function (as assessed with psychophysical testing) 1   Risk Ratio (M‐H, Fixed, 95% CI) Subtotals only
1.3.1 ≤ 4 weeks 1 77 Risk Ratio (M‐H, Fixed, 95% CI) 2.31 [1.16, 4.64]
1.4 Change in sense of smell (as assessed by participants) 2   Mean Difference (IV, Fixed, 95% CI) Subtotals only
1.4.1 At ≤ 4 weeks 1 77 Mean Difference (IV, Fixed, 95% CI) ‐0.50 [‐1.38, 0.38]
1.4.2 At > 4 weeks to 3 months 1 100 Mean Difference (IV, Fixed, 95% CI) 2.40 [1.32, 3.48]
1.5 Change in sense of smell (as assessed with psychophysical testing) 1   Mean Difference (IV, Fixed, 95% CI) Subtotals only
1.5.1 ≤ 4 weeks 1 77 Mean Difference (IV, Fixed, 95% CI) 0.20 [‐2.06, 2.46]