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. 2022 Sep 5;23:744. doi: 10.1186/s13063-022-06679-x

Table 1.

ACLF Grading using CLIF-C ACLF criteria [13, 14]

ACLF grade Criteria
No ACLF

No organ failure or

One organ failure (liver, coagulation, circulatory, respiratory) with serum creatinine <1.5mg/dL and no HE or

Single cerebral failure and serum creatinine <1.5mg/dL

Grade 1

Single kidney failure or

Single liver, coagulation, circulatory, or respiratory failure + serum creatinine 1.5–1.9mg/dL and/or HE I–II or

Single cerebral failure (HE III–IV) + serum creatinine 1.5–1.9mg/dL

Grade 2 2 organ failures
Grade 3 3 or more organ failures

mg/dL milligrammes per deciliter, HE hepatic encephalopathy