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Standard Protocol Items: Recommendations for Interventional Trials (SPIRIT) figure
t1 28 days after allocation, t2a week 6 follow-up, t3b week 12 follow-up
cChanges in liver disease severity, quality of life, and cost-effectiveness compared to standard care
d(a) Source of referral, (b) re-enrolment after unplanned hospitalisation, (c) COVID-19, and (d) hepatic decompensation without ACLF
