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. 2022 Sep 5;137(1):192–200. doi: 10.1016/j.ymgme.2022.08.009

Table 1.

IC50 values of Cysteamine HCL against wild type and major variants of SARS-CoV2. Inhibitory potency measured as IC50 was defined as the concentration of cysteamine-HCl that resulted in 50% reduction in the number of plaques compared to the untreated controls.

Virus IC50 [mM]
Wild type (Washington) 1.252
Alpha variant 1.528
Beta variant 0.799
Gamma variant 1.976
Lambda variant 0.860
Delta variant (subvariant 1) 1.066
Delta variant (subvariant 2) 1.700
Delta variant (subvariant 3) 1.373
Omicron variant (subvariant 1) 0.671
Omicron variant (subvariant 2) 1.006