Table 1.
Baseline demographic and clinical characteristics of patients.
| Early EN (n=31) | Delayed EN (n=67) | p Value | |
|---|---|---|---|
| Age, yrs | 71 (50-79) | 65 (57-71) | 0.65 |
| Female sex | 12 (38.7%) | 33 (49.3%) | 0.33 |
| Basis of gallstone etiology† | 0.58 | ||
| Gallstones or sludge | 24 (77.4%) | 53 (79.1%) | |
| Cholestasis | 13 (41.9%) | 38 (56.7%) | |
| Cholangitis | 20 (64.5%) | 36 (53.7%) | |
| Body-mass index, kg/m² | 23.7 (4.1) | 24.8 (3.4) | 0.32 |
| Disease severity | |||
| APACHE-II | 7.2 (2.9) | 7.2 (2.9) | 0.52 |
| CTSI | 2.2 (1.1) | 3.3 (2.4) | 0.11 |
| BISAP | 2.2 (0.8) | 2.3 (0.8) | 0.61 |
| CRP, mg/L | 169.0 (104.9-264.4) | 141.4 (62.2-202.8) | 0.07 |
| SIRS | 19 (61.3%) | 37 (55.2%) | 0.57 |
| Organ failure | 7 (22.6%) | 16 (23.9%) | 0.89 |
| Tests on admission to hospital | |||
| Total bilirubin, μmol/L | 28.6 (15.8-40.3) | 31.7 (17.8-54.7) | 0.27 |
| Total protein, g/L | 62.0 (55.5-67.9) | 63.2 (59.1-70.1) | 0.14 |
| Urea, mmol/L | 5.19 (3.6-6.8) | 6.5 (5.0-8.2) | 0.14 |
| White blood cell, 103/μL | 15.2 (11.7-17.3) | 12.6 (9.7-15.8) | 0.17 |
| Procalcitonin, ng/ml | 5.33 (17.3) | 5.26 (11.4) | 0.62 |
| Time from pancreatitis onset to admission, days | 2 (2-3) | 2 (1-3) | 0.84 |
| Time from admission to first ERCP, hrs | 13 (3-25) | 27 (9-64) | <0.05 |
| Time from admission to initiation of EN, hrs | 30 (15-33) | 128 (82-216) | 0.035 |
| Time from initiation of EN to initiation of oral feeding, days | 15 (14) | 16 (20) | 0.92 |
Data expressed as n (%), mean (SD), or median (IQR).
The bold values indicate that there was a significant difference.
APACHE, acute physiology and chronic health evaluation; BISAP, Bedside Index of Severity in acute pancreatitis; CRP, C-reactive protein; CTSI, computed tomography severity index; EN, enteral nutrition; ERCP, endoscopic retrograde cholangiopancreatography; SIRS, systemic inflammatory response syndrome.
†One case may involve one or more gallstone etiology.