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. 2022 Aug 22;12:972639. doi: 10.3389/fonc.2022.972639

Table 3.

Univariate logistic regression for analyzing the prognostic factors for early death.

Variable All-cause early death Cancer-specific early death
OR 95%CI P value OR 95%CI P value
Sex
 Male 1(ref) 1(ref)
 Female 1.49 0.50-4.44 0.477 1.9 0.63-5.66 0.252
Insurance status
 Insured 1(ref) 1(ref)
 Uninsured 1.36 1.14-1.62 0.001 1.24 1.04-1.49 0.02
Marital status
 Married 1(ref) 1(ref)
 Unmarried 1.19 0.90-1.56 0.217 1.32 1.00-1.75 0.049
Race
 White 1(ref) 1(ref)
 Black 0.71 0.56-0.90 0.005 0.74 0.58-0.95 0.02
 Other 1.12 0.94-1.33 0.22 1.1 0.92-1.32 0.308
Primary site
 Cardia/fundus 1(ref) 1(ref)
 Body 1.38 1.00-1.90 0.052 1.25 0.89-1.75 0.193
 Antrum/pylorus 1.57 1.25-1.98 <0.001 1.39 1.09-1.77 0.007
 Lesser/greater curvature 0.85 0.62-1.17 0.333 0.82 0.58-1.14 0.231
 Other 2.04 1.59-2.62 <0.001 1.87 1.45-2.43 <0.001
Differentiation grade
 I 1(ref) 1(ref)
 II 1.31 0.85-2.01 0.223 1.43 0.90-2.29 0.131
 III 1.65 1.1-2.49 0.016 1.89 1.21-2.95 0.005
 IV 1.99 0.97-4.07 0.06 1.93 0.90-4.12 0.09
Radiation
 No/Unknown 1(ref) 1(ref)
 Yes 1.06 0.82-1.37 0.663 1.08 0.83-1.41 0.568
Histology
 Adenocarcinoma 1(ref) 1(ref)
 Signet ring cell 1.27 0.96-1.68 0.089 1.18 0.89-1.58 0.249
 Other 0.55 0.41-0.74 <0.001 0.49 0.35-0.67 <0.001
AJCC Stage
 I 1(ref) 1(ref)
 II 0.79 0.62-1.00 0.055 0.87 0.67-1.12 0.289
 III 2.1 1.66-2.65 <0.001 2.44 1.92-3.09 <0.001
 IV 0.52 0.38-0.71 <0.001 0.53 0.38-0.74 <0.001
T stage
 T1 1(ref) 1(ref)
 T2 0.53 0.42-0.67 <0.001 0.54 0.43-0.69 <0.001
 T3 1 0.80-1.25 0.989 1.11 0.88-1.39 0.387
 T4 0.77 0.62-0.95 0.013 0.83 0.67-1.04 0.1
N stage
 N0 1(ref) 1(ref)
 N1 0.52 0.38-0.71 <0.001 0.55 0.39-0.77 <0.001
 N2 0.68 0.51-0.90 0.007 0.68 0.51-0.92 0.011
 N3 2.63 2.16-3.19 <0.001 3 2.46-3.66 <0.001
M stage
 M0 1(ref) 1(ref)
 M1 0.45 0.38-0.54 <0.001 0.36 0.30-0.44 <0.001
Surgery
 No 1(ref) 1(ref)
 Yes 0.23 0.18-0.30 <0.001 0.27 0.21-0.36 <0.001
Chemotherapy
 No/Unknown 1(ref) 1(ref)
 Yes 0.2 0.16-0.25 <0.001 0.25 0.20-0.31 <0.001
Bone metastases
 No 1(ref) 1(ref)
 Yes 1.83 1.02-3.31 0.044 1.96 1.08-3.54 0.027
Brain metastases
 No 1(ref) 1(ref)
 Yes 4.35 0.84-22.47 0.079 5.54 1.07-28.62 0.041
Liver metastases
 No 1(ref) 1(ref)
 Yes 2.64 2.04-3.40 <0.001 3.13 2.43-4.05 <0.001
Lung metastases
 No 1(ref) 1(ref)
 Yes 2.68 1.73-4.15 <0.001 2.71 1.76-4.17 <0.001

OR, odds ratio; ref, reference.