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. 2022 Sep 6;156:105292. doi: 10.1016/j.jcv.2022.105292

Table 3.

Agreements and correlation of SARS-CoV-2 antibody titer in positive samples between Abbott RBD, DiaSorin Trimeric S, Roche Elecsys and GenScript cPass assays.

Assay pair Cohen's k Spearman's rho (95% CI) Passing-Bablok average difference (95%CI)
RBD/Trimeric S 0.93 (95% CI 0.88, 0.99) 0.97 (95%CI 0.96, 0.98)* −74.95 (−10,101.94, −9952.04)⁎⁎
RBD/Elecsys 0.92 (95% CI 0.87, 0.98) 0.87 (95%CI 0.81, 0.92)* −2280.84 (−13,052.84, −8491.16)⁎⁎
RBD/cPass 0.86 (95% CI 0.78, 0.93) 0.94 (95%CI 0.90, 0.96)* 573.27 (−12,507.97, −13,654.50)⁎⁎
Trimeric S/Elecsys 0.88 (95% CI 0.81, 0.95) 0.90 (95%CI 0.86, 0.93)* −2205.89 (−11,716.78, −7304.99)⁎⁎
Trimeric S/cPass 0.88 (95% CI 0.81, 0.95) 0.94 (95%CI 0.91, 0.96)* 650.93 (−2231.08, −3532.94)⁎⁎
Elecsys/cPass 0.78 (95% CI 0.69, 0.87 s)§ 0.90 (95%CI 0.84, 0.93)* 3113.32 (−8083.30, −14,309.94)⁎⁎

Correlation is significant at p < 0.01.

⁎⁎

Average differences are significant at p < 0.05. Differences are measured in BAU/mL.

§

Cohen's kappa score of 0.7–0.8 was defined as good.

above 0.8 as excellent agreement.