Table 1.
Antimicrobial activity of Terminalia arjuna leaves and bark extract on ear pathogens determined by agar well diffusion method.
| Arjuna plant | Diameter of growth of inhibition zones (mm) |
|||||
|---|---|---|---|---|---|---|
| Staphylococcus aureus | Pseudomonas aeruginosa | Proteus mirabilis | Escherchia coli | Acitenobacter Sp. | Candida albicans | |
| Leaves extracts (mg/ml) | ||||||
| Methanol | 25.6*a ±0.57b | 16.3±0.57 | 24.6±0.57 | - | 15±0 | - |
| Ethanol | 26.3±0.57 | 15.6±0.57 | 26±0 | - | 15.3±0.57 | - |
| Acetone | 28±0 | 16±0 | 27.6±0.57 | - | 16.6±0.57 | - |
| Hot aqueous | - | - | - | - | - | - |
| Cold aqueous | - | - | - | - | - | - |
| Bark extracts (mg/ml) | ||||||
| Methanol | 23.6±0.57 | - | 15±0 | 15.6±0.57 | 17±0 | - |
| Ethanol | 26±0 | - | 14.6±0.57 | 15±0 | 16.3±0.57 | - |
| Acetone | 23.3±0.57 | - | 16.3±0.57 | 15.6±0.57 | 17.6±0.57 | - |
| Hot aqueous | 27.6±0 .57 | - | - | - | - | - |
| Cold aqueous | 26.3±0.57 | - | - | - | - | - |
| DMSO | 0 | 0 | 0 | 0 | 0 | 0 |
| Ciplox ear drop | 56.3±0.57 | 34±0 | 46.3±0.57 | 36±0 | 32.6±0.57 | nt |
| Bilva tel ear drop | 13.6±0.57 | - | 11.6±0.57 | - | - | - |
| Candid ear drop | nt | nt | nt | nt | nt | 21.3±0.57 |
-
No activity, nt = not tested.
a
Values, including diameter of the well (8mm), are means of three replicates
b
± Standard deviation. The data were analyzed by one way ANOVA followed by Dunnett's t test.
*
p<0.01 compared to positive control.