Table 3.
Distribution of MTHFR and CBS alleles among the oral cancer patients and control groups.
| Allele | Patients |
Controls |
p-value | ||||
|---|---|---|---|---|---|---|---|
| n (%) | HWE |
n (%) | HWE |
||||
| χ2 | p-value | χ2 | p-value | ||||
| MTHFR C677T | |||||||
| C | 145 (71.8) | 1.006 | 0.316 | 141 (69.1) | 0.348 | 0.555 | 0.556 |
| T | 57 (28.2) | 63 (30.9) | |||||
| MTHFR A1298C | |||||||
| A | 156 (77.2) | 0.018 | 0.893 | 150 (73.5) | 1.193 | 0.275 | 0.387 |
| C | 46 (22.8) | 54 (26.5) | |||||
| CBS 844ins68 | |||||||
| N | 176 (87.1) | 0.357 | 0.550 | 188 (92.2) | 0.260 | 0.610 | 0.096 |
| I | 26 (12.9) | 16 (7.8) | |||||
HWE, Hardy–Weinberg equilibrium; χ2, chi-square; N, non-insertion; I, insertion.