Supplementary Table 2. Hazard ratio and 95% confidence interval for CVD according to non-HDL-C levels (excluded fatal CVD cases in the first 3 years).
No. of events | Person-years | Model 1 | Model 2 | Model 3 | |
---|---|---|---|---|---|
Total CVD | |||||
Non-HDL-C (mg/dL) | |||||
<110 | 29 | 61,433 | 1.27 (0.79-2.05) | 1.44 (0.89-2.33) | 1.56 (0.96-2.54) |
110-<130 | 34 | 79,230 | 1.02 (0.65-1.61) | 1.08 (0.69-1.71) | 1.12 (0.71-1.77) |
130-<150 | 41 | 89,698 | Reference | Reference | Reference |
150-<170 | 55 | 70,670 | 1.49 (0.99-2.23) | 1.41 (0.94-2.11) | 1.38 (0.92-2.06) |
≥ 170 | 85 | 84,637 | 2.02 (1.39-2.93) | 1.81 (1.24-2.63) | 1.72 (1.18-2.51) |
Myocardial Infarction | |||||
Non-HDL-C (mg/dL) | |||||
<110 | 2 | 61,433 | 0.37 (0.08-1.68) | 0.46 (0.10-2.10) | 0.54 (0.12-2.49) |
110-<130 | 4 | 79,230 | 0.50 (0.16-1.59) | 0.55 (0.17-1.77) | 0.60 (0.19-1.91) |
130-<150 | 10 | 89,698 | Reference | Reference | Reference |
150-<170 | 20 | 70,670 | 2.20 (1.03-4.69) | 2.01 (0.94-4.31) | 1.94 (0.91-4.15) |
≥ 170 | 29 | 84,637 | 2.73 (1.33-5.60) | 2.30 (1.16-4.73) | 2.09 (1.02-4.31) |
1-SD increase | 1.60 (1.38-1.86) | 1.39 (1.20-1.61) | 1.31 (1.12-1.53) | ||
Hemorrhagic stroke | |||||
Non-HDL-C (mg/dL) | |||||
<110 | 13 | 61,433 | 2.24 (0.98-5.14) | 2.39 (1.03-5.52) | 2.37 (1.02-5.51) |
110-<130 | 16 | 79,230 | 1.92 (0.87-4.24) | 1.99 (0.90-4.40) | 1.98 (0.90-4.38) |
130-<150 | 10 | 89,698 | Reference | Reference | Reference |
150-<170 | 18 | 70,670 | 2.03 (0.94-4.41) | 1.96 (0.91-4.25) | 1.97 (0.91-4.28) |
≥ 170 | 18 | 84,637 | 1.79 (0.83-3.89) | 1.66 (0.77-3.62) | 1.71 (0.78-3.73) |
Ischemic stroke | |||||
Non-HDL-C (mg/dL) | |||||
<110 | 14 | 61,433 | 1.25 (0.63-2.46) | 1.37 (0.69-2.72) | 1.54 (0.77-3.07) |
110-<130 | 14 | 79,230 | 0.83 (0.42-1.63) | 0.87 (0.44-1.71) | 0.91 (0.46-1.80) |
130-<150 | 21 | 89,698 | Reference | Reference | Reference |
150-<170 | 15 | 70,670 | 0.78 (0.40-1.52) | 0.75 (0.39-1.46) | 0.73 (0.38-1.41) |
≥ 170 | 38 | 84,637 | 1.76 (1.03-3.00) | 1.61 (0.94-2.75) | 1.50 (0.87-2.56) |
Model 1: adjusted for age and sex
Model 2: further adjusted for smoking, BMI, hypertension, and diabetes
Model 3: further adjusted for HDL-C