Table 4.
Comparison between groups of patients with laryngeal and/or hypopharyngeal SCC submitted to TL or TPL with HT or TT – anatomopathological data.
| Variable | Thy Pos | Thy Neg | p-value |
|---|---|---|---|
| n (%) | n (%) | ||
| Invasion of adjacent structures | |||
| Pyriform sinus | 2 (13.3%) | 30 (44.1%) | 0.039a |
| Anterior commissure | 13 (86.7%) | 38 (55.9%) | 0.039a |
| Subglottis | 14 (93.3%) | 36 (52.9%) | 0.003a |
| Thyroid cartilage | 12 (80.0%) | 37 (54.4%) | 0.086 |
| Cricoid cartilage | 11 (73.3%) | 10 (14.7%) | <0.001a |
| Histological grade (degree of differentiation) | |||
| Well differentiated | 5 (33.3%) | 30 (44.1%) | 0.568 |
| Moderately well differentiated | 7 (46.7%) | 27 (39.7%) | 0.773 |
| Poorly differentiated | 3 (20.0%) | 11 (16.2%) | 0.711 |
| Angiolymphatic invasion | 0.766 | ||
| Yes | 6 (40.0%) | 23 (33.8%) | |
| No | 9 (60.0%) | 45 (66.2%) | |
| Perineural invasion | 0.474 | ||
| Yes | 4 (26.7%) | 12 (17.6%) | |
| No | 11 (73.3%) | 56 (82.4%) | |
SCC, squamous cell carcinoma; TL, total laryngectomy; TPL, total pharyngolaryngectomy; HT, hemithyroidectomy; TT, total thyroidectomy; Thy Pos, thyroid gland positive for malignancy; Thy Neg, thyroid gland negative for malignancy; SD, standard deviation.
a
Statistically significant value (p < 0.05).