Table 2. Baseline characteristics.
| Renal transplant (n = 27) | Hemodialysis (n = 39) | P-value＊ | No RRT (n = 651) | P-value† | |
|---|---|---|---|---|---|
| Age, y | 59±12 | 67±13 | 0.018 | 71±13 | ＜0.001 |
| Male | 22 (81.5) | 23 (59.0) | 0.049 | 389 (59.8) | 0.058 |
| Medical history | |||||
| Hypertension | 20 (74.1) | 34 (87.2) | 0.18 | 483 (74.2) | 0.15 |
| Diabetes mellitus | 12 (44.4) | 19 (48.7) | 0.73 | 250 (38.4) | 0.38 |
| Dyslipidemia | 14 (51.9) | 18 (46.1) | 0.65 | 308 (47.3) | 0.89 |
| Current smoking | 3 (11.1) | 3 (7.7) | 0.64 | 120 (18.5) | 0.11 |
| Atrial fibrillation | 6 (22.2) | 15 (38.5) | 0.16 | 142 (21.8) | 0.075 |
| Chronic heart failure | 2 (7.4) | 12 (30.8) | 0.016 | 65 (10.0) | 0.002 |
| Stroke | 4 (14.8) | 10 (25.6) | 0.28 | 130 (20.0) | 0.55 |
| Coronary artery disease | 2 (7.4) | 8 (20.5) | 0.13 | 92 (14.1) | 0.31 |
| Peripheral artery disease | 2 (7.4) | 8 (20.5) | 0.13 | 30 (4.6) | 0.003 |
| Investigations | |||||
| Intracranial artery | |||||
| ＞ 50% stenosis | 5 (18.5) | 13 (33.3) | 0.18 | 184 (28.4) | 0.39 |
| Extracranial artery | |||||
| ＞ 50% stenosis | 2 (7.4) | 4 (10.3) | 0.69 | 96 (14.9) | 0.37 |
| Extracranial artery | |||||
| 30%-50% stenosis | 4 (14.8) | 6 (15.4) | 0.95 | 84 (13.0) | 0.89 |
| Complex aortic atheroma | 2 (20.0) | 4 (33.3) | 0.48 | 51 (27.7) | 0.78 |
| Laboratory data | |||||
| Creatinine mg/dL | 2.4±2.5 | 7.6±2.7 | ＜0.001 | 1.0±0.6 | ＜0.001 |
| LDL-c, mg/dL | 111±41 | 98±38 | 0.18 | 117±38 | 0.009 |
| HDL-c, mg/dL | 50±22 | 51±15 | 0.74 | 55±17 | 0.12 |
| Triglycerides, mg/dL | 139±64 | 117±58 | 0.16 | 132±96 | 0.60 |
| HbA1c, % | 6.0±0.7 | 6.2±1.7 | 0.55 | 6.8±5.4 | 0.59 |
| BNP, pg/mL | 99±168 | 728±790 | ＜0.001 | 136±231 | ＜0.001 |
| Homocysteine, nmol/mL | 15.2 (11.6-19.4) | 21.5 (14.5-26.9) | 0.064 | 9.4 (7.2-12.6) | ＜0.001 |
| hsCRP, mg/mL | 1.3 (0.2-2.3) | 5.2 (1.5-14.8) | 0.44 | 1.4 (0.4-5.4) | 0.80 |
| IL-6, pg/mL | 4.0 (1.5-11.3) | 9.3 (4.3-13.5) | 0.14 | 3.5 (1.9-8.2) | 0.52 |
| NIHSS | 2 (1-4) | 4 (2-6) | 0.13 | 3 (1-5) | 0.40 |
Figures are expressed as n (%), mean±standard deviation, or median (interquartile range).
＊Comparisons between patients with renal transplant and hemodialysis.
†Comparisons among patients with renal transplant, hemodialysis, and no RRT.
Abbreviations: BNP = brain natriuretic peptide; HDL-c = high density lipoprotein cholesterol; hsCRP = high sensitivity C-reactive protein; IL-6 = interleukin-6; LDL-c = low density lipoprotein cholesterol; NIHSS = National Institute of Health Stroke Scale; RRT = renal replacement therapy.