TABLE 1.
Characteristics of adult DDLT in Japan
| Variables | n (%) or mean ± SD |
|---|---|
| Recipient factor | |
| Sex (male) | 250 (55.7) |
| Age, years | 46.3 ± 12.3 |
| Primary liver disease | |
| Acute liver failure | 112 (24.9) |
| Cirrhosis (hepatocellular, viral) | 103 (22.9) |
| Cirrhosis (hepatocellular, non‐viral) | 57 (12.7) |
| Cirrhosis (cholestatic, BA) | 30 (6.7) |
| Cirrhosis (cholestatic, non‐BA) | 92 (20.5) |
| Metabolic disease | 30 (6.7) |
| Others | 25 (5.6) |
| Re‐transplantation | 76 (16.9) |
| Ascites: Moderate | 218 (48.6) |
| Encephalopathy: ≥Ⅲ | 58 (12.9) |
| Medical condition: in ICU | 126 (28.1) |
| Dialysis | 118 (26.3) |
| Anti‐hepatitis C antibody positive | 86 (19.2) |
| BMI, kg/m2 | 23.4 ± 4.5 |
| MELD score | 23.1 ± 8.0 |
| Donor factor | |
| Sex (Male) | 263 (58.6) |
| Age, years | 44.2 ± 14.3 |
| Hypertension | 81 (18.0) |
| Diabetes mellites | 14 (3.1) |
| BMI, kg/m2 | 22.7 ± 3.9 |
| Alcohol history | 53 (12.2) |
| Smoking history | 198 (45.3) |
| Anti‐hepatitis B core antibody positive | 47 (10.5) |
| Cause of death | |
| Trauma | 84 (18.7) |
| Cerebrovascular disease | 213 (47.4) |
| Anoxia | 149 (33.2) |
| Others | 3 (0.7) |
| Duration on respirator, days | 9.9 ± 8.2 |
| Catecholamine index | 5.9 ± 7.6 |
| Sodium, maximum/ last mEq/L | 156.4 ± 10.6/ 141.0 ± 9.7 |
| Total bilirubin, maximum/ last, mg/dL | 1.9 ± 2.0/ 1.4 ± 1.7 |
| AST, maximum/ last, IU/L | 327 ± 653/ 63 ± 118 |
| ALT, maximum/ last, IU/L | 229 ± 517/ 58 ± 82 |
| GGT, maximum/ last, IU/L | 134 ± 134/ 97 ± 101 |
| Creatinine, last, mg/dL | 1.3 ± 1.6 |
| Image findings of steatosis | 45 (10.0) |
| Pathological findings | |
| Fibrosis (F0‒1/ F2/ not examined) | 250/6/193 |
| Steatosis (<30%/ ≥30%/ not examined) | 246/12/191 |
| Number of declines for donor reason ≥3 | 40 (8.9) |
| Surgical factor | |
| Split liver transplantation | 37 (8.2) |
| Simultaneous liver and kidney transplantation | 19 (4.2) |
| Total ischemic time, h | 8.9 ± 2.5 |
Data were presented as mean values ± SD and numbers (%) for continuous and categorical variables, respectively. B
Abbreviations: ALT, alanine aminotransferase; AST, aspartate aminotransferase; BA, biliary atresia; BMI, body mass index; DDLT, deceased‐donor liver transplantation; GGT, gamma‐glutamyl transpeptidase; ICU, intensive care unit; MELD, Model for End‐stage Liver Disease; SD, standard deviations.