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. Author manuscript; available in PMC: 2022 Sep 6.
Published in final edited form as: Am J Ophthalmol. 2022 May 6;241:120–129. doi: 10.1016/j.ajo.2022.04.022

TABLE 2.

Difference in Capillary Density From Optic Nerve Head Scans After Timolol Use, After Latanoprostene Bunod Use, and Between Timolol and Latanoprostene Bunod

Timolol vs Baseline P Value LBN vs Baseline P Value LBN vs Timolol P Value

Capillary density (%) (95% CI)
 Whole image −0.16 (−0.51 to 0.18) .36 0.17 (−0.19 to 0.53) .35 0.37 (−0.03 to 0.77) .07
 Peripapillary −0.11 (−0.49 to 0.28) .59 0.04 (−0.34 to 0.43) .84 0.20 (−0.24 to 0.63) .38
 Superior hemi −0.08 (−0.47 to 0.30) .68 0.09 (−0.31 to 0.48) .67 0.25 (−0.22 to 0.72) .30
 Inferior hemi −0.14 (−0.58 to 0.31) .54 −0.01 (−0.45 to 0.44) .97 0.14 (−0.33 to 0.62) .56
8-sector peripapillary capillary density (%) (95% CI)
 Nasal superior −0.19 (−0.69 to 0.32) .47 −0.03 (−0.55 to 0.48) .90 0.24 (−0.33 to 0.82) .41
 Nasal inferior −0.56 (−1.08 to −0.03) .04a 0.03 (−0.50 to 0.57) .90 0.60 (−0.02 to 1.21) .06
 Inferior nasal 0.04 (−0.62 to 0.69) .92 0.13 (−0.53 to 0.79) .70 0.07 (−0.63 to 0.77) .84
 Inferior temporal −0.08 (−0.73 to 0.58) .82 0.06 (−0.58 to 0.71) .85 0.16 (−0.57 to 0.88) .67
 Temporal inferior 0.10 (−0.47 to 0.68) .72 −0.26 (−0.86 to 0.34) .40 −0.30 (−0.94 to 0.33) .35
 Temporal superior −0.21 (−0.67 to 0.25) .38 0.11 (−0.39 to 0.60) .67 0.39 (−0.21 to 0.99) .21
 Superior temporal −0.16 (−0.76 to 0.44) .60 0.05 (−0.52 to 0.63) .85 0.28 (−0.43 to 0.98) .44
 Superior nasal 0.33 (−0.23 to 0.88) .26 0.25 (−0.28 to 0.79) .36 0.01 (−0.63 to 0.66) .96

CI = confidence interval; LBN = latanoprostene bunod.

a

Statistically significant (P < .05).