TABLE 2.
Difference in Capillary Density From Optic Nerve Head Scans After Timolol Use, After Latanoprostene Bunod Use, and Between Timolol and Latanoprostene Bunod
Timolol vs Baseline | P Value | LBN vs Baseline | P Value | LBN vs Timolol | P Value | |
---|---|---|---|---|---|---|
| ||||||
Capillary density (%) (95% CI) | ||||||
Whole image | −0.16 (−0.51 to 0.18) | .36 | 0.17 (−0.19 to 0.53) | .35 | 0.37 (−0.03 to 0.77) | .07 |
Peripapillary | −0.11 (−0.49 to 0.28) | .59 | 0.04 (−0.34 to 0.43) | .84 | 0.20 (−0.24 to 0.63) | .38 |
Superior hemi | −0.08 (−0.47 to 0.30) | .68 | 0.09 (−0.31 to 0.48) | .67 | 0.25 (−0.22 to 0.72) | .30 |
Inferior hemi | −0.14 (−0.58 to 0.31) | .54 | −0.01 (−0.45 to 0.44) | .97 | 0.14 (−0.33 to 0.62) | .56 |
8-sector peripapillary capillary density (%) (95% CI) | ||||||
Nasal superior | −0.19 (−0.69 to 0.32) | .47 | −0.03 (−0.55 to 0.48) | .90 | 0.24 (−0.33 to 0.82) | .41 |
Nasal inferior | −0.56 (−1.08 to −0.03) | .04a | 0.03 (−0.50 to 0.57) | .90 | 0.60 (−0.02 to 1.21) | .06 |
Inferior nasal | 0.04 (−0.62 to 0.69) | .92 | 0.13 (−0.53 to 0.79) | .70 | 0.07 (−0.63 to 0.77) | .84 |
Inferior temporal | −0.08 (−0.73 to 0.58) | .82 | 0.06 (−0.58 to 0.71) | .85 | 0.16 (−0.57 to 0.88) | .67 |
Temporal inferior | 0.10 (−0.47 to 0.68) | .72 | −0.26 (−0.86 to 0.34) | .40 | −0.30 (−0.94 to 0.33) | .35 |
Temporal superior | −0.21 (−0.67 to 0.25) | .38 | 0.11 (−0.39 to 0.60) | .67 | 0.39 (−0.21 to 0.99) | .21 |
Superior temporal | −0.16 (−0.76 to 0.44) | .60 | 0.05 (−0.52 to 0.63) | .85 | 0.28 (−0.43 to 0.98) | .44 |
Superior nasal | 0.33 (−0.23 to 0.88) | .26 | 0.25 (−0.28 to 0.79) | .36 | 0.01 (−0.63 to 0.66) | .96 |
CI = confidence interval; LBN = latanoprostene bunod.
Statistically significant (P < .05).