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. Author manuscript; available in PMC: 2023 Mar 1.
Published in final edited form as: Cancer Prev Res (Phila). 2022 Sep 1;15(9):595–603. doi: 10.1158/1940-6207.CAPR-22-0090

Table 4.

The associations between healthy lifestyle scores and colorectal cancer risk with adjustment for sociocultural factors and access to care.

Model 1 Model 2
Model 1 + SES
Model 3
Model 2 + access to care
Healthy Lifestyle Scorea Cohort (N) Cases (N) HR (95%CI) c HR (95%CI) d HR (95%CI) e
 0–1 21193 202 1 (ref.) 1 (ref.) 1 (ref.)
 2 30137 319 0.98 (0.82 to 1.17) 0.99 (0.83 to 1.19) 1.01 (0.85 to 1.21)
 3–4 23852 221 0.81 (0.66 to 0.99) 0.84 (0.69 to 1.03) 0.87 (0.71 to 1.06)
Healthy Lifestyle Score including BMIb
 0–1 16020 148 1 (ref.) 1 (ref.) 1 (ref.)
 2 28671 319 1.07 (0.88 to 1.31) 1.09 (0.89 to 1.32) 1.10 (0.91 to 1.35)
 3–5 30491 275 0.83 (0.68 to 1.02) 0.86 (0.70 to 1.06) 0.88 (0.71 to 1.08)

Abbreviations: CI, confidence interval; HR, hazard ratio; Ref., reference; SES, socioeconomic status.

a

“Healthy lifestyle score” is a composite variable including smoking status, alcohol, physical activity, and the ACS diet score.

b

“Healthy lifestyle score including BMI” is a composite variable including BMI, smoking status, alcohol use, physical activity, and the ACS diet score.

c

Adjusted for sex, race, enrollment source, family history of colorectal cancer.

d

Additionally adjusted for household income, education, and neighborhood deprivation.

e

Additionally adjusted for and BMI (in the Healthy Lifestyle Score model), colorectal cancer screening participation, and insurance coverage